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Bacteria directly activate sensory nerves

We know that when we are injured or have an infection, our immune system kicks into gear. This is how our body fights infection and keeps us healthy. Immune cells […]

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Is AMPK a pharmacological target for the prevention of chronic pain?

Most drugs used to treat pain are utilized because they alleviate ongoing pain or hypersensitivity produced by injury.  One very common reason people take drugs to alleviate pain is to […]

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What if pain changes the mind?

†To a friend of mine. Because her lightening mind was stronger than the pain. When trying to explain someone’s pain, we usually first look at the pain signature in the […]

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How emotions influence pain perception in chronic pain

Emotions change how we perceive pain. In healthy volunteers, positive affect is associated with reduced pain, while negative mood is associated with amplification of pain sensations (Meagher, Arnau, & Rhudy, […]

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The role of perceived injustice in chronic pain

It is increasingly recognized that the meaning individuals give to their chronic pain experience has an important influence on their pain-related adjustment. Recent research suggests that many patients with chronic […]

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Evidence about reassurance for back pain is not reassuring

Giving reassurance may be one of the most commonly used strategies for non specific low back pain (LBP) in primary care. We set out to review the evidence on reassurance […]

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It Doesn’t Have to Hurt: Strategies for Helping Children with Shots and Needles

No parent likes to take their child for shots and needles. So why is it that, despite numerous proven and accessible interventions to manage pain in children, fewer than five […]

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A good cuddle just ain’t enough!

Developmental researchers suggest that parents are hardwired to soothe their babies during distressing situations.  Much research has studied how infants and caregiver interact after the infant is distressed using a […]

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Bisphosphonates for chronic low back pain? An early test.

Bisphosphonates are well-established in the management of osteoporosis. These drugs retard bone resorption by targeting osteoclast cells. They encourage osteoclast apoptosis, a type of cell self-destruction. But bisphosphonates have been […]

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Breast pain an issue for 1 in 3 female marathon runners

The breast itself has limited support of its own and as a result moves during activity. This can result in exercise related breast pain, experienced by up to 70% of […]

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