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Neurobiology

Home / Publications / Pain Research Forum / Papers of the Week / Neurobiology
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A meta-analytic review of acceptance-based interventions for migraine.

To determine the efficacy of acceptance and mindfulness-based interventions on migraine disability, medication use, and attack frequency.

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Correlation Between Abdominal Wall Stimulation and Spinal Cord Stimulator Tip Location: A Nonrandomized Clinical Trial.

This study aimed to investigate the correlation between the vertebral level of paddle placement and abdominal wall stimulation (AWS) after differential target multiplexed spinal cord stimulation (SCS) to improve the […]

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ECAP-controlled closed-loop versus open-loop SCS for the treatment of chronic pain: 36-month results of the EVOKE blinded randomized clinical trial.

The evidence for spinal cord stimulation (SCS) has been criticized for the absence of blinded, parallel randomized controlled trials (RCTs) and limited evaluations of the long-term effects of SCS in […]

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A deep-learning driven investigation of the circuit basis for reflexive hypersensitivity to thermal pain.

Objectively measuring animal behavior is vital to understanding the neural circuits underlying pain. Recent progress in machine vision has presented unprecedented scope in behavioral analysis. Here, we apply DeepLabCut (DLC) […]

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Signal detection of adverse events associated with gabapentinoid use for chronic pain.

Gabapentinoids (GABA) prescribing as a potential and conceivably safer substitute for opioids has substantially increased. Understanding all potential adverse drug events (ADEs) associated with GABA will guide clinical decision-making for […]

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Phenotyping nociceptive, neuropathic, and nociplastic pain: who, how, & why?

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Achieving Long-Acting Local Analgesia Using an Intelligent Hydrogel Encapsulated with Drug and pH Regulator.

Local anesthetics are important for the treatment of postoperative pain. Since a single injection of the solution of a drug such as bupivacaine (BUP) works only for a few hours, […]

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Residual pain in rheumatoid arthritis: Is it a real problem?

Pain is a significant issue in Rheumatoid Arthritis (RA) and can have a negative impact on patients’ quality of life. Despite optimal control of inflammatory disease, residual chronic pain remains […]

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Repetitive and compulsive behavior after Early-Life-Pain associated with reduced long-chain sphingolipid species.

Pain in early life may impact on development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of “early-life-pain” (ELP) using mice with transgenic expression of channelrhodopsin-2 […]

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Repeated closed-head mild traumatic brain injury-induced inflammation is associated with nociceptive sensitization.

Individuals who have experienced mild traumatic brain injuries (mTBIs) suffer from several comorbidities, including chronic pain. Despite extensive studies investigating the underlying mechanisms of mTBI-associated chronic pain, the role of […]

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