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A scoping review on the availability and utilization of essential opioid analgesics in Sub-Saharan Africa.

Management of acute, post-operative, and chronic pain requires access to and availability of opioids. While often oversupplied in high-income countries, significant shortages exist in low- and middle-income countries. We conducted […]

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Translation-dependent skin hyperplasia is promoted by type 1/17 inflammation in psoriasis.

Psoriasis vulgaris (PV) is a chronic skin inflammatory disease and characterized by aberrant epidermal hyperplasia. The molecule eukaryotic initiation factor (eIF) 4E controls translation initiation of certain protein synthesis and […]

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Factors Influencing Parental Decision-making Regarding Analgesia for Children with Musculoskeletal Injury-related Pain: A Qualitative Study.

To explore and understand parental decision-making relating to acute pain management for their children presenting to the emergency department.

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Motor corticospinal excitability abnormalities differ between distinct chronic low back pain syndromes.

It is not known whether cortical plastic changes reported in low-back pain (LBP) are present in all etiologies of LBP. Here we report on the assessment of patients with three […]

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Alteration in Cortical Activity and Perceived Sensation Following Modulated TENS.

Over the last decades, conventional transcutaneous electrical nerve stimulation (TENS) has been utilized as an efficient rehabilitation intervention for alleviation of chronic pain, including phantom limb pain (PLP). However, recently […]

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Systemic opioid regimens for postoperative pain in neonates.

Postoperative pain clinical management in neonates has always been a challenging medical issue. Worldwide, several systemic opioid regimens are available for pediatricians, neonatologists, and general practitioners to control pain in […]

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Chronic pain among U.S. sexual minority adults who identify as gay, lesbian, bisexual, or “something else”.

This study assesses chronic pain prevalence among sexual minority U.S. adults who self-identify as gay/lesbian, bisexual, or “something else,” and examines the role of select covariates in the observed patterns. […]

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Paracetamol use prior to and in early pregnancy – prevalence and patterns among women with and without chronic medical diseases.

Paracetamol is commonly consumed by pregnant women, even though recent data has questioned the safety. Having chronic medical diseases (CMDs) may influence the prevalence of use during pregnancy. We aimed […]

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Are psychedelic medicines the reset for chronic pain? Preliminary findings and research needs.

Chronic pain is a leading cause of disability, reduced productivity, healthcare seeking, and a contributor to opioid overdose in the United States. For many people, pain can be satisfactorily managed […]

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Pharmacological treatments for low back pain in adults: an overview of Cochrane Reviews.

Pharmacological interventions are the most used treatment for low back pain (LBP). Use of evidence from systematic reviews of the effects of pharmacological interventions for LBP published in the Cochrane […]

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