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Serum concentrations of IL-16 and its genetic polymorphism rs4778889 affect the susceptibility and severity of endometriosis in Nigerian women.

Endometriosis is the presence of active ectopic endometrial glands and stroma at other sites outside the uterine cavity. It is a common cause of chronic pelvic pain which is sometimes […]

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Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability.

Estimating the contribution of endplate oedema known as Modic changes to lower back pain (LBP) has been the subject of multiple observational studies and reviews, some of which conclude that […]

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Aβ-CT affective touch: Touch pleasantness ratings for gentle stroking and deep pressure exhibit dependence on A-fibers.

Gentle stroking of the skin is a common social touch behavior with positive affective consequences. A preference for slow versus fast stroking of hairy skin has been closely linked to […]

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Pain tolerance after stroke: The Tromsø study.

Stroke lesions might alter pain processing and modulation by affecting the widely distributed network of brain regions involved. We aimed to compare pain tolerance in stroke survivors and stroke-free persons […]

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This Month in JAAD International: July 2023: Quality of life and itch.

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Research Progress on the Mechanisms of Central Post-Stroke Pain: A Review.

Central Post-Stroke Pain (CPSP) is a primary sequelae of stroke that can develop in the body part corresponding to the cerebrovascular lesion after stroke, most typically after ischemic stroke but […]

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Prolactin and pain of endometriosis.

Women experience chronic pain more often than men with some pain conditions being specific to women while others are more prevalent in women. Prolactin, a neuropeptide hormone with higher serum […]

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Ketamine Dose Reporting and Dose Responsiveness for Chronic Pain.

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Inhibition of T-type calcium channels with TTA-P2 reduces chronic neuropathic pain following spinal cord injury in rats.

Spinal cord injury (SCI)-induced neuropathic pain (SCI-NP) develops in up to 60-70% of people affected by traumatic SCI, leading to a major decline in quality of life and increased risk […]

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Quality of life and patient-reported symptoms in a Phase 4, real-world study of tildrakizumab in patients with moderate-to-severe psoriasis: Week 28 interim analysis.

Tildrakizumab is an anti-interleukin-23 p19 monoclonal antibody approved for the treatment of adults with moderate-to-severe plaque psoriasis. Little real-world evidence is available regarding the effects of tildrakizumab on patients’ health-related […]

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