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“Growing pains” in children and adolescents as an early symptom of migraine: A prospective study.

Children and adolescents may experience pain in the lower limbs, predominantly at the end of the day or during the night, without any relation to organic disease. These pains are […]

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Patient Delay, Lead Times, and Adherence to Diagnostic Guidelines in Children and Adolescents With Idiopathic Intracranial Hypertension.

In a cohort of 45 children and adolescents diagnosed with idiopathic intracranial hypertension (IIH), our main aims were to investigate patient delay, lead time to final diagnosis, and adherence to […]

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Reduced Cortico-Cortical Resting-State Connectivity in Sensory Systems is related to Bodily Pain in Juvenile Fibromyalgia.

Juvenile-onset fibromyalgia (JFM) is a paradigmatic chronic pain condition for which the underlying neurobiological substrates are poorly understood. This study examined for the first time data-driven resting-state functional connectivity (rsFC) […]

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Nemolizumab to target the itch-scratch cycle in paediatric atopic dermatitis.

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Peritraumatic Pain in Child Maltreatment: A Systematic Literature Review.

Extensive research has been conducted on the link between trauma, child maltreatment (CM), and chronic pain. Although the risk of suffering from chronic pain among CM survivors has been established, […]

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Sucrose analgesia for heel-lance procedures in neonates.

Sucrose has been examined for calming and pain-relieving effects in neonates for invasive procedures such as heel lance.

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MRI findings in children with migraine or tension-type headache.

Migraine and tension-type headache are common primary headaches in children. There is a risk of developing secondary headache in children. The current study was aimed to evaluate magnetic resonance imaging […]

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Breastfeeding or breast milk for procedural pain in neonates.

Pain in the neonate is associated with acute behavioural and physiological changes. Cumulative pain is associated with morbidities, including adverse neurodevelopmental outcomes. Studies have shown a reduction in changes in […]

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Repetitive and compulsive behavior after Early-Life-Pain associated with reduced long-chain sphingolipid species.

Pain in early life may impact on development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of “early-life-pain” (ELP) using mice with transgenic expression of channelrhodopsin-2 […]

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Executive Functioning and Self-Management Processes Mediate the Relationship between Insomnia and Pain-Related Disability.

Insomnia has been identified as a predictor of reduced benefit from cognitive-behavioral treatment (CBT) for adolescent chronic pain; however, it is not well understood how insomnia leads to reduced treatment […]

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