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The purpose of this study was to investigate the serum levels of mitochondrial metabolism/reactive oxygen species (ROS)-related peptides (hypoxia inducible factor-1α [HIF-1α], fibroblast growth factor-21 [FGF-21], growth differentiation factor-15 [GDF-15]) […]
Learn More >Children in acute pain often receive inadequate pain relief, partly from difficulties administering injectable analgesics. A rapid-acting, intranasal (IN) analgesic may be an alternative to other parenteral routes of administration. […]
Learn More >Acute otitis media (AOM) is one of the most common childhood infectious diseases. Pain is the key symptom of AOM and central to children’s and parents’ experience of the illness. […]
Learn More >Cognitive dysfunction associated with chronic pain may be caused by impaired synaptic plasticity. Considering the impact of silent information regulator 1 (SIRT1) on synaptic plasticity, we explored the exact role […]
Learn More >Functional dyspepsia (FD) includes postprandial distress and epigastric pain syndrome. Percutaneous electrical nerve field stimulation (PENFS) in addition to behavioral interventions (BI) has shown benefits in children with functional abdominal […]
Learn More >Although most scald burn injuries involve children under six, because of the challenges of using head mounted displays with young children there is very little research exploring the use of […]
Learn More >To summarize the available literature as well as the authors’ experience on trigeminal autonomic cephalalgias (TACs) and cranial neuralgias in children and adolescents.
Learn More >We discuss the aetiology of recurrent abdominal pain of non-organic origin, according to the Rome Criteria for Functional Gastro-intestinal Disorders and a psychogenic hypothesis. Stress activates the brain-gut-axis, which is […]
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