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Papers of the Week

Papers: 26 Aug 2023 - 1 Sep 2023

Pediatric, Review, Social Aspects

Human Studies, Neurobiology

2023 Aug 29

Cochrane Database Syst Rev



Breastfeeding or breast milk for procedural pain in neonates.


Shah PS, Torgalkar R, Shah VS


Pain in the neonate is associated with acute behavioural and physiological changes. Cumulative pain is associated with morbidities, including adverse neurodevelopmental outcomes. Studies have shown a reduction in changes in physiological parameters and pain score measurements following pre-emptive analgesic administration in neonates experiencing pain or stress. Non-pharmacological measures (such as holding, swaddling and breastfeeding) and pharmacological measures (such as acetaminophen, sucrose and opioids) have been used for analgesia. This is an update of a review first published in 2006 and updated in 2012.