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Sumatriptan as a First-Line Treatment for Headache in the Pediatric Emergency Department.

Headache is a common presenting condition for patients seen in the pediatric emergency department (ED). Intranasal (IN) sumatriptan is a well-tolerated and safe abortive treatment for migraine headache, but it […]

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Chronic pain in children and adolescents diagnosed with cancer: the challenge of mitigating the pain and the potential of integrating exercise into pain management.

Pain is one of the most common and distressing symptoms experienced by children and adolescents diagnosed with cancer. It is vital that children and adolescents receive adequate pain management early […]

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Effects of oxycodone pharmacogenetics on postoperative analgesia and related clinical outcomes in children: a pilot prospective study.

Variability in the pharmacokinetics and pharmacodynamics of oxycodone in children undergoing surgery could be due to genetic polymorphisms. The authors studied the association between clinical outcomes and pharmacogenes in children […]

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Pain and insomnia as risk factors for first lifetime onsets of anxiety, depression, and suicidality in adolescence.

Chronic pain and mental health problems have both been identified as public health emergencies and co-occur at high rates. This prospective, longitudinal investigation examined whether chronic pain status, pain-related symptoms […]

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[Complementary procedures for chronic pain disorders in childhood and adolescence].

Pain that persists or recurs over a period of at least 3 months in childhood and adolescence is referred to as chronic pain. The primary localization of pain changes according to age: […]

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Playing your pain away: designing a virtual reality physical therapy for children with upper limb motor impairment.

Children with upper limb motor impairment often undergo repetitive therapeutic physiotherapy sessions to minimize functional disabilities of the affected area. Even though therapeutic processes can improve functional outcomes and minimize […]

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The Relationship Between Chronic Pain, Depression, Psychosocial Factors, and Suicidality in Adolescents.

Chronic pain in youth is often associated with social conflict, depression, and suicidality. The Interpersonal Theory of Suicide posits that there are psychosocial factors, such as peer victimization and lack […]

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Association of Posttraumatic Headache With Symptom Burden After Concussion in Children.

Headache is the most common symptom after pediatric concussion.

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Real Life Data on OnabotulinumtoxinA for Treatment of Chronic Migraine in Pediatric Age.

The use of OnabotulinumtoxinA (OBT-A) for the treatment of chronic migraine (CM) in adults represents a therapy with the greatest efficacy and safety data. However, we have little evidence on […]

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Enhancing Exposure Treatment for Youths With Chronic Pain: Co-design and Qualitative Approach.

Increasing the access to and improving the impact of pain treatments is of utmost importance, especially among youths with chronic pain. The engagement of patients as research partners (in contrast […]

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