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Flipping the Switch in Visceral Mechanosensation

Visceral pain is a common complaint among patients with functional gastrointestinal disorders such as irritable bowel syndrome (IBS) and functional dyspepsia. It is also highly comorbid with stress-related conditions such […]

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Fallen at the First Gate: New Evidence of Inhibitory Filtering in the DRG

The dorsal horn of the spinal cord has long been seen as the major area where sensory information is first modulated. In recent years, however, there’s been increasing evidence that […]

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Open-Label Placebo Analgesia Blocked by Naloxone

Enthusiasm for the use of open-label placebos – or placebos without deception or concealment – has increased in recent years. Many factors have contributed to this increase in popularity, including […]

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Welcome to the New Home of the Pain Research Forum!

The Pain Research Forum (PRF) provides a place for the international pain research community to engage in an open exchange of information and ideas. At PRF, scientists performing basic, translational, […]

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Finally Getting to Scratch That Itch

Itch is a sensation resulting in a desire to scratch one’s skin to help remove irritants or parasites. Itch can be triggered by a variety of internal and external cues, […]

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“Papers of the Week” – Postponed Until 3 February 2023

Pain Research Forum is currently reconfiguring its backend to address particular “Papers of the Week” functionalities. We apologize for the inconvenience and will be sure to publish a double edition […]

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Pragmatic Trials versus Randomized Controlled Trials

Editor’s note: The North American Pain School (NAPS) took place 19-24 June 2022, in Montebello, Québec City, Canada. NAPS – an educational initiative of the International Association for the Study of Pain (IASP) […]

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Amazing Images of the Nervous System Receive Awards from Nikon

Each year since 1975, Nikon’s Small World has celebrated images captured by light microscope. In their 2022 Photomicrography Competition, seven images representing the dynamism of the nervous system across three […]

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The Most Popular Content of PRF in 2022

The year 2022 saw many of us finally reconnecting in person once again, highlighted by the IASP 2022 World Congress on Pain! While we all continue to adapt to our […]

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From Macrophages with Love: How Mitochondria Transfer to Nociceptors Resolves Inflammatory Pain

It’s been assumed for decades that inflammatory pain passively resolves itself once inflammation fades away. Anti-inflammatory drugs, like ibuprofen or aspirin, work on this principle – helping to reduce inflammation […]

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