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Papers of the Week

Papers: 5 Nov 2022 - 11 Nov 2022

Human Studies

2022 Nov 04

Clin Gastroenterol Hepatol

GLIMMER: A randomized Phase 2b dose-ranging trial of linerixibat in primary biliary cholangitis patients with pruritus.


Levy C, Kendrick S, Bowlus CL, Tanaka A, Jones D, Kremer AE, Mayo MJ, Haque N, von Maltzahn R, Allinder M, Swift B, McLaughlin MM, Hirschfield GM
Clin Gastroenterol Hepatol. 2022 Nov 04.
PMID: 36343847.


GLIMMER assessed dose-response, efficacy, and safety of linerixibat, an ileal bile acid transporter inhibitor in development for cholestatic pruritus associated with primary biliary cholangitis (PBC).