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Papers of the Week


Papers: 5 Nov 2022 - 11 Nov 2022


Human Studies


2022 Nov 04


Clin Gastroenterol Hepatol

GLIMMER: A randomized Phase 2b dose-ranging trial of linerixibat in primary biliary cholangitis patients with pruritus.

Authors

Levy C, Kendrick S, Bowlus CL, Tanaka A, Jones D, Kremer AE, Mayo MJ, Haque N, von Maltzahn R, Allinder M, Swift B, McLaughlin MM, Hirschfield GM
Clin Gastroenterol Hepatol. 2022 Nov 04.
PMID: 36343847.

Abstract

GLIMMER assessed dose-response, efficacy, and safety of linerixibat, an ileal bile acid transporter inhibitor in development for cholestatic pruritus associated with primary biliary cholangitis (PBC).