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Primary headache disorders: From pathophysiology to neurostimulation therapies.

Primary headache disorders including migraine, cluster headache, and tension-type headache are among the most common disabling diseases worldwide. The unclear pathogenesis of primary headache disorders has led to high rates […]

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Role of peripheral nerve stimulation in treating chronic neuropathic pain: an international focused survey of pain medicine experts.

Interventional pain management (IPM) options for refractory neuropathic pain (NP) have recently increased with availability of peripheral nerve stimulation (PNS) equipment and expertise. Given a lack of high-quality evidence and […]

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Role of neuromodulation in acute pain settings.

Peripheral nerve stimulation (PNS), a type of neuromodulatory technique, is increasingly used to treat chronic pain syndromes. PNS has also recently gained popularity as a viable adjunct analgesic modality in […]

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Trends in spinal cord stimulation utilization: change, growth and implications for the future.

Chronic pain impacts more than 100 million Americans and has a significant impact on the economy and quality of life. Spinal cord stimulation (SCS) has demonstrated efficacy in managing a growing […]

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An open-label observational study and meta-analysis of non-invasive vagus nerve stimulation in medically refractory chronic cluster headache.

Many patients with cluster headache (CH) are inadequately controlled by current treatment options. Non-invasive vagus nerve stimulation (nVNS) is reported to be effective in the management of CH though some […]

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The Choice of Spinal Cord Stimulation vs Targeted Drug Delivery in the Management of Chronic Pain: Validation of an Outcomes Predictive Formula.

In 2020, Mekhail et al published a formula that predicted the likelihood of a successful outcome for those who undergo spinal cord stimulation (SCS) for long-term pain management, based on retrospectively […]

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Neurotechnology for Pain.

Neurotechnologies for treating pain rely on electrical stimulation of the central or peripheral nervous system to disrupt or block pain signaling and have been commercialized to treat a variety of […]

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Effect of stimulation intensity of a differential target multiplexed SCS program in an animal model of neuropathic pain.

Spinal cord stimulation (SCS) has been proven to be an effective treatment for patients suffering from intractable chronic neuropathic pain. Recent advances in the field include the utilization of programs […]

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The efficacy of sensory neural entrainment on acute and chronic pain: A systematic review and meta-analysis.

Changes to the power of neural oscillations in cortical and sub-cortical structures can change pain perception. Rhythmic sensory stimulation is a non-invasive method that can increase power in specific frequencies […]

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Device profile of Nerivio for the acute and preventive treatment of episodic or chronic migraine in patients 12 years and older.

Migraine is a prevalent, inherited, disabling brain disease with multiple symptoms and a variety of treatment options. Nerivio, utilising remote electrical neuromodulation (REN) a wearable device, offers users good efficacy, […]

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