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Contactless photoplethysmography for assessment of small fiber neuropathy.

Chronic pain is a prevalent condition affecting approximately one-fifth of the global population, with significant impacts on quality of life and work productivity. Small fiber neuropathies are a common cause […]

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Chronic pain predicts a worse response to depression treatment, regardless of thyroid function or psychotropics prescribed.

Chronic pain (CP) and thyroid hormones’ (TH) abnormalities are associated with depression, but the impact of pain and TH fluctuation on the response to depression treatment is uncertain.

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Conditioned pain modulation and temporal summation of pain in patients with traumatic and non-specific neck pain: a systematic review and meta-analysis.

In patients with neck pain, it is unclear whether pain inhibition and facilitation endogenous pain mechanisms are altered. This systematic review and meta-analysis aimed improve their understanding by assessing conditioned […]

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A cholinergic circuit that relieves pain despite opioid tolerance.

Chronic pain is a tremendous burden for afflicted individuals and society. Although opioids effectively relieve pain, significant adverse outcomes limit their utility and efficacy. To investigate alternate pain control mechanisms, […]

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Pain in Parkinson’s Disease: Pathophysiology, Classification and Treatment.

Continuous medical progress is significantly improving the quality of health care. As a result, people are living longer than during the past century, but this has also caused an increase […]

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A multimodal sensing ring for quantification of scratch intensity.

An objective measurement of chronic itch is necessary for improvements in patient care for numerous medical conditions. While wearables have shown promise for scratch detection, they are currently unable to […]

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Opposing effects on descending control of nociception by mu and kappa opioid receptors in the anterior cingulate cortex.

The efficiency of descending pain modulation, commonly assessed with the conditioned pain modulation (CPM) procedure, is diminished in patients with chronic pain. We hypothesized that the efficiency of pain modulation […]

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Abdominal pain in patients with inflammatory bowel disease in remission: A prospective study on contributing factors.

Abdominal pain is highly prevalent in patients with inflammatory bowel disease (IBD) in remission, but the aetiology is incompletely understood.

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Changes in cognitive appraisal in a randomized controlled trial of mindfulness-based cognitive therapy for patients with migraine.

This study is a secondary analysis evaluating changes in cognitive fusion and pain catastrophizing over 8 weeks of mindfulness-based cognitive therapy for migraine (MBCT-M) intervention versus waitlist/treatment as usual.

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Menstrual migraine is caused by estrogen withdrawal: revisiting the evidence.

To explore and critically appraise the evidence supporting the role of estrogen withdrawal in menstrual migraine.

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