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Neurobiology

Home / Publications / Pain Research Forum / Papers of the Week / Neurobiology
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Neuroplasticity of pain processing and motor control in CAI patients: A UK Biobank study with clinical validation.

Pain plays an important role in chronic ankle instability (CAI), and prolonged pain may be associated with ankle dysfunction and abnormal neuroplasticity.

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Virtual Reality: A New Treatment Paradigm for Disorders of Gut-Brain Interaction?

Disorders of gut-brain interaction (DGBIs), previously called functional bowel disorders, are prevalent, reduce patients’ quality of life, and impose a significant negative economic impact on the health care system. Functional […]

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Mouse models of surgical and neuropathic pain produce distinct functional alterations to prodynorphin expressing neurons in the prelimbic cortex.

The medial prefrontal cortex (mPFC) consists of a heterogeneous population of neurons that respond to painful stimuli, and our understanding of how different pain models alter these specific mPFC cell […]

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Athletes and Nonathletes Show No Difference in Symptoms or Function Prior to Knee Surgery, but Those With Chronic Symptoms Show Increased Pain Catastrophizing and Kinesiophobia.

To determine whether preoperative psychological status before outpatient knee surgery is influenced by athletic status, symptom chronicity, or prior surgical history.

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Regional Coverage Differences With Single- and Multiarea Burst Spinal Cord Stimulation for Treatment of Chronic Pain.

Burst spinal cord stimulation (SCS) has shown superior relief from overall pain and a reduction in back and leg pain compared with traditional tonic neurostimulation therapies. However, nearly 80% of […]

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Astrocytic purinergic signaling contributes to the development and maintenance of neuropathic pain via modulation of glutamate release.

Although activation of astrocytes is critical in developing neuropathic pain (NP) following nerve injury, the underlying mechanisms of NP and therapeutic management for NP are still vague. Importantly, the decreases […]

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Effect of temporal frequency on habituation in migraine.

Individuals with migraine tend to experience discomfort when viewing flickering stimuli. It has been suggested that one of the characteristics of migraine is a lack of habituation to repetitive visual […]

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Systemic inflammatory markers in patients with polyneuropathies.

In patients with peripheral neuropathies (PNP), neuropathic pain is present in 50% of the cases, independent of the etiology. The pathophysiology of pain is poorly understood, and inflammatory processes have […]

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Low-dose celecoxib-loaded PCL fibers reverse intervertebral disc degeneration by up-regulating CHSY3 expression.

Intervertebral disc degeneration (IDD) has been identified as one of the predominant factors leading to persistent low back pain and disability in middle-aged and elderly people. Dysregulation of Prostaglandin E2 […]

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Investigation of Pain Sensitivity Following 3 Nights of Disrupted Sleep in Healthy Individuals.

Poor quality sleep is a common complaint among people with chronic pain. The co-occurrence of poor sleep quality and chronic pain often comes with increased pain intensity, more disability, and […]

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