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Human Studies

Home / Publications / Pain Research Forum / Papers of the Week / Human Studies
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Improving the Management of Postdural Puncture Headache-An International Clinical Guideline and Call for Better Evidence.

An Update on Temporomandibular Disorders (TMDs) and Headache.

To provide an overview and highlight recent updates in temporomandibular disorders (TMDs) and their comorbidity with headache disorders regarding pathophysiology and management.

Patient experience of spontaneous intracranial hypotension (SIH): qualitative interviews for concept elicitation.

Spontaneous intracranial hypotension (SIH) is an underdiagnosed and debilitating condition caused by a spinal cerebrospinal fluid (CSF) leak. Although SIH can lead to substantial morbidity and disability, little data exists […]

Photophobia Contributes to Migraine-Associated Disability and Reduced Work Productivity: Results From the American Registry for Migraine Research (ARMR).

Photosensitivity, often called “photophobia” in the migraine literature, is a common and bothersome symptom for most people during their migraine attacks. This study aimed to investigate the association of photophobia […]

Occupational mechanical exposures as risk factor for chronic low-back pain: a systematic review and meta-analysis.

The association between occupational mechanical exposures and low-back pain (LBP) has been studied in several systematic reviews. However, no systematic review addressing chronic LBP exists. The aim of this systematic […]

Role of Cav2.3 (R-type) Calcium Channel in Pain and Analgesia: A Scoping Review.

Voltage-gated calcium channels (VGCCs) play an important role in pain development and maintenance. As Cav2.2 and Cav3.2 channels have been identified as potential drug targets for analgesics, the participation of […]

Intrapatient comparison of atopic dermatitis skin transcriptome shows differences between tape-strips and biopsies.

Our knowledge of etiopathogenesis of atopic dermatitis (AD) is largely derived from skin biopsies, which are associated with pain, scarring and infection. In contrast, tape-stripping is a minimally invasive, nonscarring […]

Nocebo Response Intensity and Influencing Factors in the Randomized Clinical Trials of Functional Dyspepsia: A Systematic Review and Meta-analysis.

The nocebo effect, a phenomenon that pertains to the negative impacts experienced by patients due to their negative expectations, is not connected to the physiological mechanism of the treatment in […]

Effects of exercise/physical activity on fear of movement in people with spine-related pain: a systematic review.

Kinesiophobia (i.e., fear of movement) can be an important contributor for ongoing pain and disability in people with spine-related pain. It remains unclear whether physical activity interventions/exercise influence kinesiophobia in […]

Abnormal brain activity in lumbar disc herniation patients with chronic pain is associated with their clinical symptoms.

Lumbar disc herniation, a chronic degenerative disease, is one of the major contributors to chronic low back pain and disability. Although many studies have been conducted in the past on […]

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