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Papers of the Week
Role of Cav2.3 (R-type) Calcium Channel in Pain and Analgesia: A Scoping Review.
Authors
de Amorim Ferreira M, Ferreira JAbstract
Voltage-gated calcium channels (VGCCs) play an important role in pain development and maintenance. As Cav2.2 and Cav3.2 channels have been identified as potential drug targets for analgesics, the participation of Cav2.3 (that gives rise to R-type calcium currents) in pain and analgesia remains incompletely understood.