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Online dynamic nomogram for predicting pain recurrence after microvascular decompression in trigeminal neuralgia.

Trigeminal neuralgia (TN) is one of the most common causes of facial pain. Microvascular decompression (MVD) is the first-choice surgical treatment. The present study aimed to develop a novel practical […]

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A multimodal meta-analysis of gray matter alterations in trigeminal neuralgia.

Brain gray matter alterations in patients with trigeminal neuralgia (TN) have been detected in prior neuroimaging studies, but the results are heterogeneous. The current study conducted coordinate-based meta-analyses across neuroimaging […]

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Defining Personas of People Living with Chronic Pain: An Ethnographic Research Study.

Pain is the leading reason for which people seek medical care in the United States, and chronic pain (CP) affects approximately 50 million people in the US Pain perception is […]

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Feasibility and acceptability to use a smartphone-based manikin for daily longitudinal self-reporting of chronic pain.

As management of chronic pain continues to be suboptimal, there is a need for tools that support frequent, longitudinal pain self-reporting to improve our understanding of pain. This study aimed […]

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Intranasal analgesia for acute moderate to severe pain in children – a systematic review and meta-analysis.

Children in acute pain often receive inadequate pain relief, partly from difficulties administering injectable analgesics. A rapid-acting, intranasal (IN) analgesic may be an alternative to other parenteral routes of administration. […]

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Patients with cluster headache show signs of insomnia and sleep related stress: results from an actigraphy and self-assessed sleep study.

Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often […]

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Advanced brain MRI may help understand the link between migraine and multiple sclerosis.

There is a clinical association between migraine and multiple sclerosis.

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The impact of temperature on the skin barrier and atopic dermatitis.

Climate change is a global threat to public health and causes/worsens various diseases including atopic dermatitis (AD), allergic, infectious, cardiovascular diseases, physical injuries and mental disorders. The incidence of allergy, […]

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Janus Effect of the Anterior Cingulate Cortex: Pain and Emotion.

Over the past 20 years, clinical and preclinical studies point to the anterior cingulate cortex (ACC) as a site of interest for several neurological and psychiatric conditions. The ACC plays […]

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Pain-motor integration in chronic pain: A neurophysiological study.

Chronic pain may lead to functional changes in several brain regions, including the primary motor cortex (M1). Our neurophysiological study aimed to probe M1 plasticity, through a non-invasive transcranial magnetic […]

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