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The timing and magnitude of improvements in depression, anxiety, disability, and pain intensity during an internet-delivered program for chronic pain.

Numerous studies have found that pain management programs are an effective treatment option for people with chronic pain. However, little is known about when people experience improvements during these programs, […]

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Parkinson disease-related pains are not equal: clinical, somatosensory and cortical excitability findings in individuals with nociceptive pain.

Chronic pain is a frequent and burdensome non-motor symptom of Parkinson Disease (PD). PD-related chronic pain can be classified as nociceptive, neuropathic or nociplastic, the former being the most frequent […]

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Efficacy and safety of transdermal buprenorphine for acute postoperative pain: A systematic review and meta-analysis.

Transdermal buprenorphine (TBUP) may have some advantages for the management of acute postoperative pain. The aim of this systematic review and meta-analysis was to investigate the efficacy and safety of […]

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Inflammasome in Skeletal Muscle: NLRP3 Is an Inflammatory Cell Stress Component in Inclusion Body Myositis.

Inclusion body myositis (IBM) is a chronic, mostly treatment-resistant, inflammatory myopathy with a pathology that centers around specific interactions between inflammation and protein accumulation. The study aimed to identify the […]

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The Natural History of Knee Osteoarthritis Pain Experience and Risk Profiles.

The study aimed to characterize the natural history of pain experience, concurrently considering intermittent and constant pain over 4 years and determine baseline factors associated with unfavorable trajectories in individuals […]

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Metabolic Biomarkers Differentiate a Surgical Intervertebral Disc from a Nonsurgical Intervertebral Disc.

Degeneration of the intervertebral disc (IVD) is caused by disturbances in metabolic processes, which lead to structural disorders. The aim of this report is to analyze metabolic disorders in the […]

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Pain Catastrophizing: Controversies, Misconceptions and Future Directions.

Recent reports have pointed to problems with the term ‘pain catastrophizing’. Critiques of the term pain catastrophizing have come from several sources including individuals with chronic pain, advocates for individuals […]

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State of the Art in Temporomandibular Joint Arthrocentesis-A Systematic Review.

Temporomandibular joint disorders are a heterogenic group of clinical conditions, which impair physiological functioning of the masticatory system. Arthrocentesis of the temporomandibular joint has become a widely approved method for […]

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Developmental impact of peripheral injury on neuroimmune signaling.

A peripheral injury drives neuroimmune interactions at the level of the injury and throughout the neuraxis. Understanding these systems will be beneficial in the pursuit to target persistent pain that […]

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Usability and acceptability of virtual reality for chronic pain management among diverse patients in a safety-net setting: a qualitative analysis.

The aim of this study was to understand the usability and acceptability of virtual reality (VR) among a racially and ethnically diverse group of patients who experience chronic pain.

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