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Papers of the Week


Papers: 15 Jul 2023 - 21 Jul 2023

RESEARCH TYPE:
Clinical


Human Studies, Molecular/Cellular, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Inflammation/Inflammatory, Itch


2023 Jul 13


J Allergy Clin Immunol


37453614

Oral difelikefalin reduces moderate-to-severe pruritus and expression of pruritic and inflammatory biomarkers in subjects with atopic dermatitis.

Authors

Guttman-Yassky E, Facheris P, Da Rosa JC, Rothenberg-Lausell C, Duca ED, David E, Estrada Y, Liu Y, Bose S, Chowdhury M, Munera C, Goncalves J, Nograles K, Kim BS, Lebwohl M

Abstract

Pruritus is the most common and burdensome symptom of atopic dermatitis (AD). Pruritus-targeted treatments in AD are lacking, particularly for patients with milder skin disease.