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Pain Commentary on Spinal hyperexcitability in patients with chronic musculoskeletal pain or headache as evidenced by alterations in the nociceptive withdrawal reflex: a systematic review and meta-analysis.

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Developing Monosodium Urate Monohydrate Crystals-Induced Gout Model in Rodents and Rabbits.

Gout is a chronic disease caused by the deposition of monosodium urate monohydrate (MSU) crystals within the body, particularly in one or more joints, which can lead to sudden severe […]

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A self-assembling peptide-based hydrogel containing NF-B inhibitors and NGF for peripheral nerve injury repair.

An inflammatory response may be initiated after peripheral nerve injury (PNI), potentially hindering the repair and regeneration of damaged nerves. Administering anti-inflammatory agents to modulate macrophage phenotypes may reduce post-injury […]

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Red flags in multiple sclerosis.

The diagnosis of multiple sclerosis (MS) is often challenging and misdiagnosis remains an important contemporary problem, with considerable consequences for patients. This review aims to specify the appropriate approach in […]

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Engagement in Digital Self-management Interventions for Chronic Pain: A Systematic Review.

Digital interventions promise to increase access to non-pharmacological chronic pain treatment and reduce burden for both individuals seeking care and pain providers/clinics. Unfortunately, despite early evidence of efficacy, engagement in […]

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The Convergent Validity of Pain Drawings and Anatomical Checklists in Individuals with Chronic Pain.

The assessment of the spatial characteristics of pain, such as location and extent, is essential in the clinical evaluation of pain syndromes, especially when managing patient’s with chronic musculoskeletal pain. […]

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Fear-avoidance beliefs are associated with changes of back shape and function.

Psychosocial function in people with chronic low back pain (cLBP) is often impaired, indicating poor well-being. Fear-avoidance beliefs (FAB) are common concomitants of cLBP. Fear-avoidance beliefs are gaining attention as […]

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Oral pH- and inflammation-targeted delivery system with biodegradable multi-layer core-shell nanocapsules for the treatment of ulcerative colitis.

Most biologics require administration parenteral routes; however, the pain and local allergic reaction brought about by injection usually lead to poor compliance, especially for chronic patients. Meanwhile, the oral delivery […]

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Profiling chronic migraine patients according to clinical characteristics: a cluster analysis approach.

To group the characteristics of chronic migraine (CM) by headache characteristics.

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Melittin: A Promising Therapeutic Agent for Rheumatoid Arthritis Treatment.

Rheumatoid Arthritis (RA) is a globally prevalent chronic disease that presents significant challenges in terms of curability. The etiology and onset of RA are not readily identifiable, and as the […]

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