Accepted

Opioid use disorder (OUD) is a chronic relapsing disorder. The brain adapts to opioids along pain treatment or recreational use, so that abstinence becomes a true challenge for individuals with […]

Mechanical chronic low back pain is often associated with impaired neuromuscular control of the lumbar multifidus muscles, the most important stabilizers of the lumbar spine. Restorative neurostimulation is a modality […]

Most hospitalized patients with inflammatory bowel disease (IBD) experience pain. Despite the known risks associated with opioids in IBD including risk for misuse, overdose, infection, readmission, and even death, opioid […]

Chronic pain is a common, complex, and challenging condition, for which specialised healthcare is required. We investigated the relationship between multisite chronic pain (MCP) and different disease traits identify safe […]

Chronic pancreatitis (CP) causes an abdominal pain syndrome associated with poor quality of life (QOL). We conducted a clinical trial to further investigate the efficacy and safety of camostat, an […]

Atopic dermatitis (AD) is predominantly characterized by intense itching, but concomitant skin pain is experienced by more than 40% of patients. Patients with AD display considerable somatosensory aberrations including increased […]

Patients with chronic pain commonly report impaired memory. Increasing evidence has demonstrated that inhibition of neurogenesis by neuroinflammation plays a crucial role in chronic pain-associated memory impairments. There is currently […]

Migraine is a highly prevalent neurological disorder, with prevalence rates ranging from 9% to 18% worldwide. Current pharmacological prophylactic strategies for migraine have limited efficacy and acceptability, with relatively low […]

The majority of research on the long-term effects of spinal cord injury (SCI) has primarily focused on neuropathic pain (NP), psychological issues, and sensorimotor impairments. Among SCI patients, mood disorders, […]