Browse by Audience
Previous research has shown that type 1 interferons (IFN), such as IFN-α and IFN-ß, possess antiviral and antinociception effects. Elevated levels of microRNA-29a (miR-29a) have been observed during inflammatory pain, […]
Learn More >Serum neurofilament light chain (sNfL) levels are an increasingly employed tool for the assessment of active axonal injury in a variety of neurological disorders including polyneuropathy. Injury to the small […]
Learn More >Migraine is one of the most prevalent and disabling neurological diseases, significantly affecting quality of life and productivity, as well as contributing to substantial societal costs. Recent innovations, including calcitonin […]
Learn More >Inflammatory myopathy with abundant macrophage [IMAM] is marked by macrophage infiltration and muscle fibers damage, resembling dermatomyositis [DM] but with unique pathology. Its mechanism remains unclear. Our study focused on […]
Learn More >Traumatic brain injury (TBI) commonly elicits acute (APTH) and/or persistent (PPTH) post-traumatic headache. Calcitonin gene related peptide (CGRP) has been implicated as a contributor to PTH pathophysiology. We explored the […]
Learn More >Research has identified that individuals with chronic pain comfort eat in response to their pain, however, little is known about the function that comfort eating serves for chronic pain patients. […]
Learn More >Osteoarthritis (OA) is the most common form of arthritis, affecting over 500 million people globally. Current treatments are primarily symptom-focused, with no approved therapies to halt disease progression. Glucagon-like peptide-1 […]
Learn More >Pulpitis is a prevalent oral disease characterized by severe pain. The activation of microglia in the medullary dorsal horn (MDH) is reportedly essential for the central sensitization mechanism associated with […]
Learn More >Neurological diseases are a significant contributor to premature mortality and temporary or long-term disability among survivors. Asia serves as an essential region for assessing the shifting burden of these disorders. […]
Learn More >Cutaneous neurofibroma (cNF) presenting with pain and itch substantially affects the quality of life. The CXCL10/CXCR3 axis, a well-known chemokine signaling pathway involved in pain and itch transmission, has recently […]
Learn More >