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Papers of the Week
Enhanced CXCL10 expression in mast cells for cutaneous neurofibroma presenting with pain and itch.
Authors
Pham TTQ, Liao CP, Shih YH, Lee WR, Liao YH, Chou CL, Chiu YW, Liu D, Wang HC, Chen BJ, Shao YJ, Yeh TS, Lai KH, Weng HJAbstract
Cutaneous neurofibroma (cNF) presenting with pain and itch substantially affects the quality of life. The CXCL10/CXCR3 axis, a well-known chemokine signaling pathway involved in pain and itch transmission, has recently been implicated in neurofibroma development. Our study aims to investigate the expression patterns and potential roles of the CXCL10/CXCR3 axis in pain and itch associated with cNFs.