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Accepted

Home / Publications / Pain Research Forum / Papers of the Week / Accepted
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NGF in Neuropathic Pain: Understanding Its Role and Therapeutic Opportunities.

Nerve growth factor (NGF) is one of the essential components that have been implicated in the pathophysiology of neuropathic pain, a condition that develops following nerve injury or dysfunction. This […]

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Prescription opioid use and cognitive function in older adults with chronic pain: A population-based longitudinal cohort study.

Whether prescription opioid exposure, duration, and dose are associated with cognitive function remains inconclusive.

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Association between headache frequency and risk for fibromyalgia in patients with migraine.

The present study aimed to evaluate the risk and impact of fibromyalgia in relation to headache frequency in migraine patients.

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Combined effects of cannabidiol and Δ9-tetrahydrocannabinol alleviate migraine-like symptoms in mice.

The therapeutic use of cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) to treat migraine has been understudied. Using three mouse models, we examined the impact of CBD and THC on migraine-relevant behaviors […]

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Pregnenolone sulfate potentiates tetrodotoxin-resistant Na channels to increase the excitability of dural afferent neurons in rats.

Although peripheral administration of pregnenolone sulfate (PS) has been reported to produce pronociceptive effects, the mechanisms by which PS modulates the excitability of nociceptive neurons are poorly understood. Here, we […]

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Alpha-2 receptor mediates the endogenous antagonistic regulation of itch and pain via descending noradrenaline pathway from the locus coeruleus.

Pain and itch are sensations that are regulated antagonistically; painful stimulation suppresses itch, while the inhibition of pain enhances itch. However, the central neural circuit underlying this antagonistic regulation remains […]

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Interactive effects of morphine and the HIV integrase inhibitor, cabotegravir, in male and female mice.

Cabotegravir is a novel therapeutic option for HIV prevention. Similar to the opioid morphine, cabotegravir, undergoes glucuronidation through the enzymes uridine diphosphate glucuronosyltransferase (UGT) in the liver. We hypothesize that […]

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Psychedelic-assisted Therapy as a Promising Treatment for Irritable Bowel Syndrome.

Irritable bowel syndrome (IBS) is prevalent and can be disabling. Many patients remain symptomatic despite behavioral and medical therapies. Psychedelic-assisted therapy (PAT), in which serotonergic agents like psilocybin are administered […]

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Addressing Pain and Heavy Drinking among Patients in HIV-Care: A Pilot Study of an Integrated Telehealth Intervention.

Chronic pain is common among people living with HIV (PLWH) who engage in heavy drinking and both pain and heavy drinking influence quality of life, functioning, and HIV-outcomes. The purpose […]

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Review: An Update on CGRP Monoclonal Antibodies for the Preventive Treatment of Episodic Migraine.

CGRP targeting therapies have revolutionized the migraine preventive space, introducing novel migraine-specific therapies to improve headache care. Four monoclonal antibodies (mAbs) are approved for use in prevention of episodic migraines. […]

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