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Virtual Reality in Acute and Chronic Pain Medicine: An Updated Review.

This review critically analyzes the recent literature on virtual reality’s (VR) use in acute and chronic pain management, offering insights into its efficacy, applications, and limitations.

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Sexually dimorphic effects of pexidartinib on nerve injury-induced neuropathic pain in mice.

It is well-established that spinal microglia and peripheral macrophages play critical roles in the etiology of neuropathic pain; however, growing evidence suggests sex differences in pain hypersensitivity owing to microglia […]

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Harnessing spectra of pain psychology treatment design to improve patient access to care.

Darnall BD, Burns JW, Hong J, Roy A, Slater K, Poupore-King H, Ziadni MS, You DS, Jung C, Cook KF, Lorig K, Tian L, Mackey SC. Empowered relief, cognitive behavioral […]

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Research hotspots and trends on acupuncture treatment for headache: a bibliometric analysis from 2003 to 2023.

While acupuncture treatment has gained extensive usage in addressing headaches, there remains a notable gap in the literature analysis for this field. Therefore, this study aims to conduct a literature […]

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Large-scale real-world data on a multidisciplinary approach to spinal cord stimulation for persistent spinal pain syndromes: first evaluation of the Neuro-Pain nationwide screening and follow-up interactive register.

Spinal cord stimulation is a common treatment option for neuropathic pain conditions. Despite its extensive use and multiple technological evolutions, long term efficacy of spinal cord stimulation is debated. Most […]

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Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes.

Gene expression is influenced by chromatin architecture via controlled access of regulatory factors to DNA. To better understand regulation of gene expression in the human dorsal root ganglion (hDRG) we […]

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Parabrachial Calca neurons drive nociplasticity.

Pain that persists beyond the time required for tissue healing and pain that arises in the absence of tissue injury, collectively referred to as nociplastic pain, are poorly understood phenomena […]

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Comprehensive plasma cytokine and chemokine profiling in prurigo nodularis reveals endotypes in Type 2 inflammation.

Prurigo nodularis (PN) is a chronic inflammatory skin disease that is associated with variability in peripheral blood eosinophil levels and response to T-helper 2 targeted therapies (Th2). Our objective was […]

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Changes in Resting-State Brain Activity after Cognitive Behavioral Therapy for Chronic Pain: A Magnetoencephalography Study.

Cognitive Behavioral Therapy (CBT) is believed to be an effective treatment for chronic pain due to its association with cognitive and emotional factors. Nevertheless, there is a paucity of magnetoencephalography […]

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The effectiveness of hypnoanalgesia using conventional and placebo hypnosis induction.

The effectiveness of hypnosis-based pain management is well established. However, mechanisms of action and specific effective components are not well understood. The socio-cognitive theory of hypnosis proposes that the effectiveness […]

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