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Carpal tunnel syndrome.

Carpal tunnel syndrome (CTS) is the most common nerve entrapment disorder worldwide. The epidemiology and risk factors, including family burden, for developing CTS are multi-factorial. Despite much research, its intricate […]

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Beyond Vertigo: Vestibular, Aural, and Perceptual Symptoms in Vestibular Migraine.

To review the vestibular, aural, and perceptual symptoms of vestibular migraine (VM) that may present alongside vertigo.

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Functional impairment of chronic migraine with medication overuse: Secondary analysis from the Medication Overuse Treatment Strategy (MOTS) trial.

Chronic migraine exerts substantial negative impacts on daily functioning. Efforts to manage impaired functioning may result in medication overuse, which contributes to the worsening profile and chronification of migraine. The […]

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Beyond aura: Understanding migraine as a cycling pan-sensory threshold disease.

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Biomarker development perspective: Exploring comorbid chronic pain in depression through deep transcranial magnetic stimulation.

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Antioxidant supplementation for sickle cell disease.

Sickle cell disease (SCD) refers to a group of genetic disorders characterized by the presence of an abnormal haemoglobin molecule called haemoglobin S (HbS). When subjected to oxidative stress from […]

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A comprehensive review on ziconotide.

Managing severe chronic pain is a challenging task, given the limited effectiveness of available pharmacological and non-pharmacological treatments. This issue continues to be a significant public health concern, requiring a […]

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Methylene blue dose-dependently induces cutaneous inflammation and heat hyperalgesia in a novel rat model.

Methylene blue (MB) has been shown to reduce mortality and morbidity in vasoplegic patients after cardiac surgery. Though MB is considered to be safe, extravasation of MB leading to cutaneous […]

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Response to Letter to the Editor: “Measurement of Pain Frequency Associated with Knee Osteoarthritis: Future Directions”.

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Neurobiological mechanisms of botulinum neurotoxin-induced analgesia for neuropathic pain.

Botulinum neurotoxins (BoNTs) are a family of neurotoxins produced by Clostridia and other bacteria that induce botulism. BoNTs are internalized into nerve terminals at the site of injection and cleave […]

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