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Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). Demyelination in the CNS provokes hyperalgesia, negative emotions, and/or cognitive impairment. Cuprizone (CPZ)-induced demyelination is a major […]
Learn More >Migraine is a common condition that can cause intense headaches, often on one side of the head, along with symptoms like nausea and sensitivity to light and sound. These headaches […]
Learn More >This chapter will review the basic pharmacology of the canonical cannabinoid receptors. The endocannabinoid system is a complex signalling network involved in a wide range of physiological processes, including pain […]
Learn More >Spiking neural networks (SNNs) present the potential for ultra-low-power computation, especially when implemented on dedicated neuromorphic hardware. However, a significant challenge is the efficient conversion of continuous real-world data into […]
Learn More >Virtual reality (VR) is a promising intervention for both experimentally induced and clinical pain, but the factors contributing to the efficacy of VR remain relatively unclear, partially because selecting adequate […]
Learn More >Once taken into consideration, sex differences in neurological diseases emerge in abundance: (i) Stroke severity is significantly higher in females than in males, (ii) Alzheimer’s disease (AD) pathology is more […]
Learn More >ConspectusThe author presents his personal story from early contributions in purinergic receptor research to present-day structure-guided medicinal chemistry. Modulating purinergic signaling (encompassing pyrimidine nucleotides as well) and other nucleoside targets […]
Learn More >Green-synthesized nanoparticles provide an eco-friendly approach to nanotechnology, reducing harmful chemical use and environmental impact. This study focuses on the green synthesis of nickel oxide nanoparticles (FV-NiO NPs) using Fioria […]
Learn More >The presence and prognosis of nerve pathology following whiplash injury: a prospective cohort study.
Whiplash Associated Disorders (WAD) affect 20-50 million individuals globally each year, with up to 50% developing persistent pain. WAD grade II (WADII) is the most common type and is characterised […]
Learn More >Intervertebral disc degeneration (IDD) is one of the most common diseases in the elderly population. Recently, immune disorders have been considered to play an important role in IDD. This study […]
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