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Different Patterns of Autoantibody Secretion by Peripheral Blood Mononuclear Cells in Autoimmune Nodopathies.

Autoimmune nodopathies with antibodies against the paranodal proteins show a distinct phenotype of a severe sensorimotor neuropathy. In some patients, complete remission can be achieved after treatment with rituximab whereas […]

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Chronic Itch Affects Patients’ Ability to Experience Pleasure: Anhedonia in Itchy Disorders.

Anhedonia, the reduced ability to experience pleasure, is a prevalent symptom in various psychiatric disorders, but has not been investigated in dermatological conditions, particularly those characterized by chronic itch. This […]

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Exploring the Biomarkers and Potential Mechanisms of Botulinum Toxin Type A in the Treatment of Microglial Inflammatory Activation through P2X7 Receptors based on Transcriptome Sequencing.

This study aims to explore the potential mechanism by which Botulinum toxin type A (BoNT/ A) inhibits microglial inflammatory activation through P2X7 receptors (P2X7R).

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Commentary on Yang et al.: The need for a renewed focus on identifying and responding to chronic pain among people with substance use disorders.

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Topical amitriptyline in burning mouth syndrome: A retrospective real-world evidence study.

To evaluate the effectiveness, tolerability, and safety of topical amitriptyline as a potential route of administration for the management of burning mouth syndrome.

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Advancing toward precision migraine treatment: Predicting responses to preventive medications with machine learning models based on patient and migraine features.

To develop machine learning models using patient and migraine features that can predict treatment responses to commonly used migraine preventive medications.

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Headache activity associated with the 2024 North American eclipse.

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Predictive and concurrent validity of pain sensitivity phenotype, neuropeptidomics and neuroepigenetics in the MI-RAT osteoarthritic surgical model in rats.

Micro-RNAs could provide great insights about the neuropathological mechanisms associated with osteoarthritis (OA) pain processing. Using the validated ontreal nduction of at rthritis esting (MI-RAT) model, this study aimed to […]

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From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn’s disease and ulcerative colitis.

Inflammatory bowel disease (IBD) is a common chronic inflammatory bowel disease characterized by diarrhea and abdominal pain. Recently human metabolites have been found to help explain the underlying biological mechanisms […]

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Quantitative Electroencephalography and Balance Test Correlations in Patients with Chronic Patellofemoral Pain.

Quantitative Electroencephalography (QEEG) is a tool helping better understand the electrical activity of the brain and a non-invasive method to assess cortical activity. To date, the brain activity of patients […]

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