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Accepted

Home / Publications / Pain Research Forum / Papers of the Week / Accepted
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Efficacy of Roflumilast Foam, 0.3%, in Patients With Seborrheic Dermatitis: A Double-blind, Vehicle-Controlled Phase 2a Randomized Clinical Trial.

Current topical treatment options for seborrheic dermatitis are limited by efficacy and/or safety.

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Association Between Depression and Physical Conditions Requiring Hospitalization.

Depression is associated with an increased risk of physical illness, but the most common causes of hospitalization among people with depression are unclear.

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Mental disorder prevalence in chronic pain patients using opioid versus non-opioid analgesics: A registry-linkage study.

Chronic pain and mental disorders are leading causes of disability worldwide. Individuals with chronic pain are more likely to experience mental disorders compared to individuals without chronic pain, but large-scale […]

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The mTOR inhibitor rapamycin suppresses trigeminal neuropathic pain and p-MKK4/p-p38 mitogen-activated protein kinase-mediated microglial activation in the trigeminal nucleus caudalis of mice with infraorbital nerve injury.

Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. We previously demonstrated that the mammalian target of […]

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Sustained response of galcanezumab in migraine prevention: Patient-level data from a post hoc analysis in patients with episodic or chronic migraine.

To evaluate, at population and individual patient levels, the sustained response of reduction in migraine headache days in patients with migraine treated with galcanezumab.

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The relationship between major depression and migraine: A bidirectional two-sample Mendelian randomization study.

Previous epidemiological and other studies have shown an association between major depressive disorder (MDD) and migraine. However, the causal relationship between them remains unclear. Therefore, this study aimed to investigate […]

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Effects of risk factors on evoked pain patterns in rat models of experimental knee osteoarthritis.

Pain experiences in patients with knee osteoarthritis (OA) may be influenced differently by OA risk factors, reducing the translatability of pre-clinical research into the clinic. Our objective was to contrast […]

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Psychedelics as Transformative Therapeutics.

Over the past decade, psychedelic compounds have emerged as potentially transformative therapeutics for a variety of intractable neuropsychiatric conditions. However, historically most of the basic science has utilized these compounds […]

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The Role of Opioid Receptors in Cancer.

Opioids are one of the most potent drugs for treating moderate to severe pain. Despite irrefutable clinical application in chronic pain management, the long-term use of opioids has been increasingly […]

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Epigenomic profiling of mouse nucleus accumbens at single-cell resolution.

The nucleus accumbens (NAc) is a key brain region involved in reward processing and is linked to multiple neuropsychiatric conditions such as substance use disorder, depression, and chronic pain. Recent […]

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