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Clinical, Neurophysiologic, and Pathologic Features in Patients With Early Onset Post-Radiation Neuropathy.

To study early-onset radiation-induced neuropathy reviewing neurologic course, steroid-response, and available nerve biopsies.

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Migraine prevention: initial treatment options.

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A qualitative exploration of chronic pain management of older adults in remote and rural settings.

The World Health Organization predicts that the number of older adults will nearly double between 2015 and 2050. Older adults are at a higher risk of developing medical conditions such […]

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Effect of static magnetic field therapy on diabetic neuropathy and quality of life: a double-blind, randomized trial.

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM) that can cause annoying symptoms. To address this condition, several treatment approaches have been proposed, including static magnetic […]

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A Brief Review on the Novel Therapies for Painful Diabetic Neuropathy.

Almost half of people diagnosed with diabetes mellitus will develop painful diabetic neuropathy (PDN), a condition greatly impacting quality of life with complicated pathology. While there are different FDA approved […]

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CC chemokines and receptors in osteoarthritis: new insights and potential targets.

Osteoarthritis (OA) is a prevalent degenerative disease accompanied by the activation of innate and adaptive immune systems-associated inflammatory responses. Due to the local inflammation, the expression of various cytokines was […]

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Microglia are involved in regulating histamine-dependent and non-dependent itch transmissions with distinguished signal pathways.

Although itch and pain have many similarities, they are completely different in perceptual experience and behavioral response. In recent years, we have a deep understanding of the neural pathways of […]

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Comparative efficacy of different treatments for menstrual migraine: a systematic review and network meta-analysis.

Menstrual migraine is a subtype of migraine disease that is typically more disabling, longer-lasting, and more challenging to treat. The purpose of this network meta-analysis (NMA) is to compare the […]

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Clinical Features and Natural History of Paediatric Patients with Ulcerative Proctitis: A Multicentre Study from the Paediatric IBD Porto Group of ESPGHAN.

Ulcerative proctitis (UP) is an uncommon presentation in paediatric patients with ulcerative colitis. We aimed to characterize the clinical features and natural history of UP in children, and identify predictors […]

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Real-world evidence on the economic implications of CGRP-mAbs as preventive treatment of migraine.

Calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) are approved in Europe as preventive treatment of migraine in patients with at least four monthly migraine days. Migraine gives rise to direct […]

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