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How Treatment Motivation Predicts Favorable Outcomes in Interdisciplinary Multimodal Pain Treatment Among Patients with Chronic Primary Pain.

As motivation for psychological treatment at intake has been shown to predict favorable outcomes after an inpatient stay, this study aimed to further characterize the different components of psychological treatment […]

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Automatic extraction of social determinants of health from medical notes of chronic lower back pain patients.

We applied natural language processing and inference methods to extract social determinants of health (SDoH) information from clinical notes of patients with chronic low back pain (cLBP) to enhance future […]

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Psychiatric risk factors for chronic high-dose opioid prescribing: register-based cohort study.

Chronic high-dose (CHD) prescription opioid use is a major public health concern. Although CHD opioid use has been associated with psychiatric disorders, the causality could go both ways. Some studies […]

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Repeated gentle handling or maternal deprivation during the neonatal stage increases adult male rats’ baseline orofacial pain responsiveness.

Early life experiences have been found to have a long-lasting effect on brain development in adult life. The purpose of this study was to determine whether neonatal manipulation could alter […]

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The role of time interval elimination on pain control of preterm infants by sucrose administration.

The 2-min time interval of sucrose administration given before minor painful procedures in preterm infants is based on a few limited studies. We aimed to assess availability of sucrose analgesia […]

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Red induces hyperalgesia and white induces hypoalgesia regardless of pain modality.

Colors are an important factor that influences different aspects of people’s lives. However, little is known about the effects of colors on pain. This preregistered study aimed to investigate whether […]

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Acanthoscurria gomesiana spider-derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid.

Depression has a high rate of comorbidity with neuropathic pain. This study aims to investigate the effect of Mygalin, an acylpolyamine synthesized from a natural molecule in the hemolymph of […]

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Use of pain-related gene features to predict depression by support vector machine model in patients with fibromyalgia.

The prevalence rate of depression is higher in patients with fibromyalgia syndrome, but this is often unrecognized in patients with chronic pain. Given that depression is a common major barrier […]

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Chinese and Indian interpretations of pain: A qualitative evidence synthesis to facilitate chronic pain management.

People from minority ethnicities often have a greater impact of chronic pain, are underrepresented at pain services, and may not benefit from treatment to the same extent as dominant cultures. […]

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Sleep quality as a mediator of the relation between depression and chronic pain: a systematic review and meta-analysis.

Chronic pain and depression represent two global health problems with considerable economic consequences. Although existing literature reports on the relation between depression and pain conditions, meta-analytic evidence backing the mediating […]

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