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Papers of the Week


Papers: 15 Apr 2023 - 21 Apr 2023

RESEARCH TYPE:
Psychology, Review


Human Studies, Neurobiology

PAIN TYPE:
Psychological/Comorbidities


2023 Apr 12


Br J Anaesth


37059623

Sleep quality as a mediator of the relation between depression and chronic pain: a systematic review and meta-analysis.

Authors

Karimi R, Mallah N, Scherer R, Rodríguez-Cano R, Takkouche B

Abstract

Chronic pain and depression represent two global health problems with considerable economic consequences. Although existing literature reports on the relation between depression and pain conditions, meta-analytic evidence backing the mediating role of sleep disturbance as one of the main symptoms of depression is scarce. To examine the extent to which sleep disturbance mediates the depression-chronic pain association, we conducted a systematic review and meta-analysis of the associations of chronic pain, depression, and sleep quality.