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Causal relationships between migraine and microstructural white matter: a Mendelian randomization study.

Migraine is a disabling neurological disorder with the pathophysiology yet to be understood. The microstructural alteration in brain white matter (WM) has been suggested to be related to migraine in […]

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Do MRI-derived muscle moment-arms in patients with chronic low back pain differ from healthy individuals? A comparative study.

The present study aimed to estimate the trunk muscles moment-arms in low back pain (LBP) patients and compare this data to those of healthy individuals. This research further explored whether […]

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The relationship between headache-attributed disability and lost productivity: 3 Attack frequency is the dominating variable.

In an earlier paper, we examined the relationship between headache-attributed disability, measured as proportion of time in ictal state, and lost productivity. In a linear model, we found positive and […]

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HIV-PASS (Pain and Sadness Support): Randomized controlled trial of a behavioral health intervention for interference due to pain in people living with HIV, chronic pain, and depression.

To determine whether HIV-Pain and Sadness Support (HIV-PASS), a collaborative behavioral health intervention based on behavioral activation, is associated with decreased pain-related interference with daily activities, depression, and other outcomes […]

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Wearable nanocomposite sensor system for motion phenotyping chronic low back pain: a BACPAC Technology Research Site.

Chronic low back pain (cLBP) is a prevalent and multifactorial ailment. No single treatment has been shown to dramatically improve outcomes for all cLBP patients, and current techniques of linking […]

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Probiotics for management of functional abdominal pain disorders in children.

Functional abdominal pain is pain occurring in the abdomen that cannot be fully explained by another medical condition and is common in children. It has been hypothesised that the use […]

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Post-surgical contributors to persistent knee pain following knee replacement: The Multicenter Osteoarthritis Study (MOST).

Pain persistence following knee replacement (KR) occurs in ∼20-30% of patients. Although several studies have identified preoperative risk factors for persistent post-KR pain, few have focused on post-KR contributing factors. […]

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A study of differential microRNA expression profile in migraine: the microMIG exploratory study.

Several studies have described potential microRNA (miRNA) biomarkers associated with migraine, but studies are scarcely reproducible primarily due to the heterogeneous variability of participants. Increasing evidence shows that disease-related intrinsic […]

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Changes in migraine interictal burden following treatment with galcanezumab: Results from a phase III randomized, placebo-controlled study.

To evaluate changes in interictal burden with galcanezumab versus placebo in patients with episodic (EM) or chronic migraine (CM).

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Fecal microbiota transplantation revealed a pain-related gut microbiota community in ovariectomized mice.

Higher sensitivity to pain is a common clinical symptom in postmenopausal females. The gut microbiota (GM) has recently been identified as participating in various pathophysiological processes and may change during […]

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