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Papers of the Week


Papers: 18 Feb 2023 - 24 Feb 2023

RESEARCH TYPE:
Clinical


Human Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Musculoskeletal Pain, Psychological/Comorbidities


2023 Mar


Osteoarthr Cartil Open


36798734


5


1

Post-surgical contributors to persistent knee pain following knee replacement: The Multicenter Osteoarthritis Study (MOST).

Authors

Aoyagi K, Law LF, Carlesso L, Nevitt M, Lewis CE, Wang N, Neogi T

Abstract

Pain persistence following knee replacement (KR) occurs in ∼20-30% of patients. Although several studies have identified preoperative risk factors for persistent post-KR pain, few have focused on post-KR contributing factors. We sought to determine whether altered nociceptive signaling and other peripheral nociceptive drivers present post-operatively contribute to post-KR pain.