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Papers of the Week
Causal relationships between migraine and microstructural white matter: a Mendelian randomization study.
Authors
Zhao L, Zhao W, , Cao J, Tu YAbstract
Migraine is a disabling neurological disorder with the pathophysiology yet to be understood. The microstructural alteration in brain white matter (WM) has been suggested to be related to migraine in recent studies, but these evidence are observational essentially and cannot infer a causal relationship. The present study aims to reveal the causal relationship between migraine and microstructural WM using genetic data and Mendelian randomization (MR).