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Automatic extraction of social determinants of health from medical notes of chronic lower back pain patients.

We applied natural language processing and inference methods to extract social determinants of health (SDoH) information from clinical notes of patients with chronic low back pain (cLBP) to enhance future […]

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Long COVID and especially headache syndromes.

This is an expert overview on recent literature about the complex relationship between coronavirus disease 2019 (COVID-19) and headache.

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Psychiatric risk factors for chronic high-dose opioid prescribing: register-based cohort study.

Chronic high-dose (CHD) prescription opioid use is a major public health concern. Although CHD opioid use has been associated with psychiatric disorders, the causality could go both ways. Some studies […]

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Rimegepant 75 mg in Subjects With Hepatic Impairment: Results of a Phase 1, Open-Label, Single-Dose, Parallel-Group Study.

Rimegepant is a small-molecule calcitonin gene-related peptide receptor antagonist (gepant) with demonstrated efficacy and safety in the acute and preventive treatment of migraine. Here, we report the pharmacokinetics and safety […]

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Non-steroidal anti-inflammatory drugs-aspirin interactions and with risk of cardiovascular disease in patients osteoarthritis.

Non-steroidal anti-inflammatory drugs (NSAIDs) remain the mainstay of the pharmacologic management for relieving osteoarthritis (OA) pain and low-dose aspirin is often prescribed to OA patients who are at high risk […]

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Emerging Systemic Treatments for Atopic Dermatitis.

Atopic dermatitis (AD) is a chronic or chronically relapsing inflammatory skin disease which results from a complex, multifaceted interaction between environmental factors in genetically predisposed patients. Epidermal barrier impairment, alteration […]

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Repeated gentle handling or maternal deprivation during the neonatal stage increases adult male rats’ baseline orofacial pain responsiveness.

Early life experiences have been found to have a long-lasting effect on brain development in adult life. The purpose of this study was to determine whether neonatal manipulation could alter […]

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Red induces hyperalgesia and white induces hypoalgesia regardless of pain modality.

Colors are an important factor that influences different aspects of people’s lives. However, little is known about the effects of colors on pain. This preregistered study aimed to investigate whether […]

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Safety of topical medications in the management of pediatric atopic dermatitis: an updated systematic review.

There have been new topical agents developed for the treatment of atopic dermatitis in recent years. This systematic review is intended to synthesize the clinical trial literature and concisely report […]

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Efficacy and Safety of Tralokinumab in Adolescents With Moderate to Severe Atopic Dermatitis: The Phase 3 ECZTRA 6 Randomized Clinical Trial.

Safe and effective long-term treatments for adolescents with moderate to severe atopic dermatitis (AD) are limited.

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