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Papers of the Week


2023 Mar


Am J Ophthalmol Case Rep


29

Minimally invasive corneal neurotization for neurotrophic keratopathy: The potential effect of age, denervation chronicity and lesion location.

Authors

Ting DSJ, Pradhan SP, Barnes E, Ahmed OA, Figueiredo FC
Am J Ophthalmol Case Rep. 2023 Mar; 29:101804.
PMID: 36718433.

Abstract

Neurotrophic keratopathy (NK) is an uncommon but challenging clinical condition characterized by altered corneal nerves and sensation leading to corneal damage. Corneal neurotization, a surgical technique that aims to "re-innervate" the cornea, has gained increasing popularity in view of the potential to permanently improve or even restore the normal corneal sensation. In this study, we aimed to report the outcomes of two cases of NK that underwent indirect minimally invasive corneal neurotization (MICN) with a sural nerve autograft, and to provide plausible explanations for the observed clinical outcomes.