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Papers of the Week


2022 Jul 02


Endocrine

Psychological complications in patients with acromegaly: relationships with sex, arthropathy, and quality of life.

Authors

Cangiano B, Giusti E, Premoli C, Soranna D, Vitale G, Grottoli S, Cambria V, Mantovani G, Mungari R, Maffei P, Dassie F, Giampietro A, Chiloiro S, Tanda M L, Ippolito S, Cannavò S, Ragonese M, Zambon A, Persani L, Fatti L M, et al.
Endocrine. 2022 Jul 02.
PMID: 35779206.

Abstract

Current treatment of acromegaly restores a normal life expectancy in most cases. So, the study of persistent complications affecting patients' quality of life (QoL) is of paramount importance, especially motor disability and depression. In a large cohort of acromegalic patients we aimed at establishing the prevalence of depression, to look for clinical and sociodemographic factors associated with it, and to investigate the respective roles (and interactions) of depression and arthropathy in influencing QoL.