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Papers of the Week


2021 May 06


Photodiagnosis Photodyn Ther

SEQUENTIAL TREATMENT OF CALCITRIOL AND METHYL AMINOLEVULINATE-DAYLIGHT PHOTODYNAMIC THERAPY IN PATIENTS WITH MULTIPLE ACTINIC KERATOSES OF THE UPPER EXTREMITIES.

Authors

Piaserico S, Piccioni A, Garcìa-Rodrigo C G, Sacco G, Pellegrin C, Fargnoli M C
Photodiagnosis Photodyn Ther. 2021 May 06:102325.
PMID: 33965603.

Abstract

Topical photodynamic therapy (PDT) is a widely used effective treatment for actinic keratoses (AKs). However, cure rates are significantly reduced for AKs on acral sites. We compared the sequential regimen of topical calcitriol and methyl aminolevulinate (MAL) daylight-PDT (CAL-DL-PDT) versus placebo and MAL-DL-PDT (P-DL-PDT) on acral AKs in an intra-individual, randomized trial.