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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / [Involvement of Pirt /TRPV1 signaling in acupuncture-induced reduction of visceral hypersensitivity in diarrhea-predominant irritable bowel syndrome rats].

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2021 Apr 25


Zhen Ci Yan Jiu


http://www.ncbi.nlm.nih.gov/pubmed/33931991?dopt=Abstract


46


4

[Involvement of Pirt /TRPV1 signaling in acupuncture-induced reduction of visceral hypersensitivity in diarrhea-predominant irritable bowel syndrome rats].

Authors

[Involvement of Pirt /TRPV1 signaling in acupuncture-induced reduction of visceral hypersensitivity in diarrhea-predominant irritable bowel syndrome rats].
Chen Y, Zhao Y, Wang L, Yao J-P, Li Y, Zhou S-Y
Zhen Ci Yan Jiu. 2021 Apr 25; 46(4):278-83.
PMID: 33931991.

Abstract

To observe the effect of electroacupuncture (EA) on the expression of Pirt (a regulator of TRPV1) in the dorsal root ganglia (DRG) and transient receptor potential vanilloid 1 (TRPV1, a molecular sensor of noxious heat and capsaicin) in the colonic mucosa in rats suffering from diarrhea-predominant irritable bowel syndrome (IBS-D), so as to explore its mechanisms underlying alleviation of visceral hypersensitivity of IBS-D.
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