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Papers of the Week


Papers: 20 Feb 2021 - 26 Feb 2021


Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2021 Feb 18


Headache

Systematic review of outcomes and endpoints in preventive migraine clinical trials.

Authors

McGinley JS, Houts CR, Nishida TK, Buse DC, Lipton RB, Goadsby PJ, Dodick DW, Wirth RJ
Headache. 2021 Feb 18.
PMID: 33600610.

Abstract

Over the last six decades (earliest included publication from 1959), clinical trials of migraine preventive treatments have led to the regulatory approval of many medications and devices. Despite similar clinical goals, the outcomes and endpoints used in these trials are broad and not well standardized.