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Papers of the Week


Papers: 18 Apr 2020 - 24 Apr 2020


Animal Studies

PAIN TYPE:
Itch


2020 Apr 20


J Neuroinflammation


17


1

Spinal cord NLRP1 inflammasome contributes to dry skin induced chronic itch in mice.

Authors

Fan J-J, Gao B, Song A-Q, Zhu Y-J, Zhou J, Li W-Z, Yin Y-Y, Wu W-N
J Neuroinflammation. 2020 Apr 20; 17(1):122.
PMID: 32312281.

Abstract

Dry skin itch is one of the most common skin diseases and elderly people are believed to be particularly prone to it. The inflammasome has been suggested to play an important role in chronic inflammatory disorders including inflammatory skin diseases such as psoriasis. However, little is known about the role of NLRP1 inflammasome in dry skin-induced chronic itch.