PRF News

Patients and doctors alike know that sleep and pain present something of a vicious cycle: Pain makes sleeping difficult, and losing sleep makes pain worse. But the brain mechanisms behind […]

Open any college neuroscience textbook to the chapter on sensory perception and you’ll quickly learn that you can’t tickle yourself, no matter how hard you try (and chances are, upon […]

Damage to peripheral nerves sets in motion a series of events that facilitate the removal of neuronal debris following Wallerian degeneration and promote the regeneration of axons. But this can […]

The experience of pain includes both sensory and affective components. Pain researchers have learned a lot about the former—about the peripheral mechanisms by which noxious stimuli are transduced into electrical […]

The response to a painful stimulus generally consists of two phases: a quick withdrawal from the stimulus, followed by behaviors such as rubbing or licking of the injured area to […]

As preclinical pain research increasingly includes both female and male animals, sex differences in pain are becoming more and more apparent. New work from Jeffrey Mogil, McGill University, Montreal, Canada, […]

Editor's Note: Since publication of this article, WHO adopted ICD-11, including the new classification system for chronic pain developed by the IASP Task Force. Read the IASP press release here. […]

The vast majority of pain research focuses on neurons, and to a much lesser extent glia, but new research now shows that the extracellular matrix (ECM), the supportive milieu outside […]