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Papers of the Week
The Safety of Celecoxib as an Acute Treatment for Migraine: A Narrative Review.
Authors
Ailani J, Nahas SJ, Friedman DI, Kunkel TAbstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the first-line choice for the acute treatment of migraine attacks for decades; however, the safety of a particular NSAID is related to its treatment dose, duration, and mechanism of action. Although adverse event (AE) risks differ substantially among individual migraine treatments, increased or prolonged exposure to any NSAID elevates risks and severity of AEs.