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Papers of the Week


Papers: 8 Apr 2023 - 14 Apr 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Medical Devices, Molecular/Cellular, Neuromodulation, Pharmacology/Drug Development

PAIN TYPE:
Cancer Pain, Neuropathic Pain


2023 Apr 11


Neuromodulation


37045646

Spinal Cord Stimulation Increases Chemoefficacy and Prevents Paclitaxel-Induced Pain via CX3CL1.

Authors

Sivanesan E, Sanchez KR, Zhang C, He SQ, Linderoth B, Stephens KE, Raja SN, Guan Y

Abstract

Despite increasing utilization of spinal cord stimulation (SCS), its effects on chemoefficacy, cancer progression, and chemotherapy-induced peripheral neuropathy (CIPN) pain remain unclear. Up to 30% of adults who are cancer survivors may suffer from CIPN, and there are currently no effective preventative treatments.