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Papers of the Week


Papers: 14 Dec 2024 - 20 Dec 2024


2024 Dec 11


Int Immunopharmacol


39672030


145

Salicylalazine: A novel therapeutic agent targeting TLR4/NLRP3/GSDMD-mediated pyroptosis in rheumatoid arthritis.

Authors

Qasim S, Al-Joufi FA, Uttra AM, Afzal HS, Ahmed SR

Abstract

Joint pain and functional impairment are hallmarks of arthritis, a painful inflammatory disease. Salicylalazine (SAZ), an anti-inflammatory compound, has demonstrated promise in modulating inflammation, thereby being selected in the current study to unveil its anti-arthritic potential.