S1P/S1PRs-TRPV4 axis is a novel therapeutic target for persistent pain and itch in chronic dermatitis.
Authors
Zhang X, Zhou Y, Wang C, Ren J, Wang Y, Liu P, Feng W, Li X, Qi M, Yang Y, Zhu C, Wang F, Ma Y, Tang Z, Yu G
Abstract
While pain and itch are both commonly associated with chronic dermatitis (CD), the molecular mechanisms underlying these debilitating symptoms is not well understood. This study aims to identify novel, endogenous compounds that mediate CD-associated pain and itch.
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