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Papers of the Week
Reduced Spinal Cord Gray Matter in Patients with Fibromyalgia Using Opioids Long-term.
Authors
Baker AK, Park SH, Weber KA, Martucci KTAbstract
Chronic pain involves alterations in brain gray matter volume (GMV). Moreover, opioid medications are known to reduce GMV in numerous brain regions involved in pain processing. However, no research has evaluated (1) chronic pain-related GMV alterations in the spinal cord or (2) the effect of opioids on spinal cord GMV. Accordingly, this study evaluated spinal cord GMV in health controls and patients with fibromyalgia who were using and not using opioids long-term.