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Papers of the Week

Papers: 9 Dec 2023 - 15 Dec 2023

2023 Dec 08

J Transl Med




Ozone alleviates MSU-induced acute gout pain via upregulating AMPK/GAS6/MerTK/SOCS3 signaling pathway.


Fan W, Liu C, Chen D, Xu C, Qi X, Zhang A, Zhu X, Liu Y, Wang L, Hao L, Liu WT, Hu L


Gout pain seriously affects the quality of patients’ life. There is still no effective treatment. The inflammatory response is the main mechanism of gout. Here, we found that ozone can reduce the inflammatory reaction in the joints of gouty mice and relieve gout pain, and we further explore its protective mechanism.