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Papers: 20 May 2023 - 26 May 2023
RESEARCH TYPE:
Basic Science
Animal Studies, Molecular/Cellular, Neurobiology, Pharmacology/Drug Development
PAIN TYPE:
Migraine/Headache, Psychological/Comorbidities
2023 May 25
J Headache Pain
24
1
Migraine is a highly disabling health burden with multiple symptoms; however, it remains undertreated because of an inadequate understanding of its neural mechanisms. Neuropeptide Y (NPY) has been demonstrated to be involved in the modulation of pain and emotion, and may play a role in migraine pathophysiology. Changes in NPY levels have been found in patients with migraine, but whether and how these changes contribute to migraine is unknown. Therefore, the purpose of this study was to investigate the role of NPY in migraine-like phenotypes.